Ever thought your allergy-triggering mast cells could become cancer’s worst nightmare? Chinese researchers just flipped the script, engineering these immune warriors to spark inflammation right inside tumors, waking up the body’s defenses.
Zhejiang University and First Hospital of China Medical University teams modified mast cells with cancer-targeting antibodies, turning them into tumor-seeking missiles that unleash controlled “allergic” heat—making sneaky cancers visible and vulnerable to attack.
These cells smuggle oncolytic viruses past immune patrols, releasing cancer-killers only at the tumor site. Personalized magic: tailor to patient markers, load with drugs or nanotech—future combos with immunotherapies could revolutionize treatment.
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